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This Lewy body dementia patient was initially expressionless, she became more responsive after consuming Scallop-derived PLASMALOGEN for 2 weeks. The hallucinations that she used to experience have also disappeared.
This semantic dementia patient (characterized by loss of word meaning) showed improvement from moderate to mild dementia through MMSE, a test commonly used to screen for dementia.
This Alzheimer’s patient showed dramatic improvement just 1 month after taking Scallop-derived PLASMALOGEN.
Follow the footsteps of Mr. Fuji to explore the benefits of Scallop-derived PLASMALOGEN on patients with Alzheimer’s and dementia. This Thai documentary was broadcasted on Thailand’s National TV. The Scallop-derived PLASMALOGEN featured in this trial is in the jelly form, while the commercial version is in a capsule form (for better protection of the integrity of the substance).
Did you know?
Statistics from Alzheimer’s Disease International record an approximate 44 million people worldwide living with Alzheimer’s disease or related dementia in 2016. Did you know that 1 in 10 Singaporean adults aged 60 and above has dementia (WiSE study Institute of Mental Health, IMH). According to Alzheimer’s Disease Association, Singapore, the number of dementia cases will increase dramatically every year due to the ageing population.
Before Symptoms Appear!
A study shows that the accumulation of Aβ protein (amyloid plaque) in brain, started as early as 20 years before the appearance of symptoms of Alzheimer’s disease. This means that if a person is diagnosed with Alzheimer’s disease at the age of 65, the changes in the brain have started 20 years ago (around age 45).
The causes of Alzheimer’s disease are still unidentified but research suggests they probably include a combination of genetic, environmental and lifestyle factors (e.g. brain fatigue). In fact, two abnormal structures, namely amyloid plaques and neurofibrillary tangles (deposits of tau proteins) in the brain are prime suspects of nerve cells damage that could possibly lead to Alzheimer’s disease.
What are amyloid plaques?
Like dental plaques that form on teeth, amyloid plaques are clusters of Aβ protein deposits in the brain. In a healthy brain, the proteins would be broken down and removed from the brain naturally. However, in an Alzheimer’s diseased brain, the body is unable to remove these protein fragments and they accumulate to form hard and insoluble plaques between the neurons (nerve cells) in the brain. This causes disruption to neurons communication and induces oxidative stress that affects the proper functioning of the brain.
What are neurofibrillary tangles?
Brain cells depend on an internal transport system to carry nutrients and other essential compunds throughout the extensive neural network. This system requires the normal structure protein called tau. In Alzheimer's disease, threads of tau protein twist into abnormal tangles inside brain cells, leading to failure of the transport system and causing death of brain cells.
Alzheimer’s may also be attributed to brain fatigue. Recent studies in Japan found that one of the possible root causes of dementia is “Stress-induced Brain Fatigue”. Excessive stress coupled with unhealthy lifestyle and diets, environment contaminants and lack of sleep, produce free radicals, thereby causing the nerve cells to oxidise and the brain to fall into a state of fatigue. This may lead to symptoms of dementia over a prolonged period.
Plasmalogens are a type of phospholipid present in almost all tissues of human, and are most abundant in the brain. They are essential for their critical role in memory, focus and other cognitive functions. Plasmalogen levels in the body begin to increase from foetal stage, peak by the 30s and start to decline thereafter. Research indicated that this decline affects brain performance, especially in plasmalogen-deficient seniors.
Breakthrough in Plasmalogen Research
The strong correlation between plasmalogens and Alzheimer’s disease had already been confirmed decades ago. However, these studies had made very little progress. The main reason for the slow progression was due to extraordinary amount of time and money required for plasmalogen extraction and detection. In addition, there was no high-volume extraction technology available to extract large amount of plasmalogens for animal testing and clinical trial. However, a research team led by Emeritus Professor, Takehiko Fujino of Kyushu University in Japan has successfully established a simple plasmalogen detection method and developed a patented plasmalogen extraction method to extract large volumes of high purity (92%) plasmalogens. These discoveries have led to a major breakthrough in plasmalogen research.
Studies have also shown that plasmalogen levels are significantly reduced in the brain tissue and serum of Alzheimer’s disease patients. The decline of plasmalogen is associated with the severity of cognitive impairment.
Plasmalogens are available from many sources of food. However, studies have proven that the structure of Scallop-derived PLASMALOGEN is closest to that of the plasmalogens found in the human body. In addition, plasmalogen from scallop is found to have better and quicker effects than chicken-derived plasmalogens in the improvement of cognitive fuction of dementia patients.
A promising life-changer for Alzheimer’s sufferers
Alzheimer’s not only affects patients, it is also hard on the caregivers especially since the condition progresses in severity as time goes by.
Intensive clinical studies by researchers in Japan have confirmed positive results of Scallop-derived PLASMALOGENS in improving cognitive functions of Alzheimer’s patients! This amazing discovery brings a new hope to Alzheimer’s patients and their loved ones.
Subject C: 80 year-old male, dementia of Alzheimer’s type for 3 years
Although the symptom of repeating activities continues, he began to actively enjoy life after consuming Scallop-derived PLASMALOGEN for 3 months. He took part in ball games at the elderly club, invited friends for a meal and grew vegetables in the garden. His MMSE score also improved by 5 points in 3 months.
Subject D: 70 year-old female, dementia of Alzheimer’s type for 11 years
She suffered from severe delusion and could not take care of herself. Changes were seen two months after she consumed scallop-derived PLASMALOGEN. She was able to apply lipstick and put on accessories without any help. This reduced the burden on her husband as her caregiver.
Subject E: 70 year-old male, dementia of Alzheimer’s type for 1 year
He became irritable due to his inability to carry out his daily tasks. His skill in “Go” (Chinese board game) slackened from level 6 to the beginner’s level. Changes were observed after he consumed Scallop-derived PLASMALOGEN. He became more cheerful and empathetic. He recovered and his skill in “Go” was reinstated to level 6. Now he volunteers and teaches “Go” at a day service facility.
Superior Qualities of NeuroREGAIN
NeuroREGAIN is highly recommended for:
1. Bateman, R. J. et al. 2012. Clinical and biomarker changes in dominantly inherited Alzheimer’s disease. N. Engl. J. Med. 367(9): 795-804.
2. Braverman,N.E. & Moser, A.B 2012. Function of plasmalogen lipids in health and disease. Biochimica et Biophysica Acta. 1822:1442-1452.
3. Goodenowe, D.B. et al. 2007. Peripheral ethanolamine plasmalogen deficiency: a logical causative factor in Alzheimer’s disease and dementia. J. Lipid Res. 48: 2485–2498.
4. Guan, Z., et al. 1999. Decrease and structural modifications of phosphatidylethanolamine plasmalogen in the brain with Alzheimer disease. J. Neuropathol. Exp. Neurol. 58: 740–747.
5. Katafuchi, T. et al. 2012. Effects of plasmalogens on systemic lipopolysaccharide-induced glial activation and β-amyloid accumulation in adult mice. Ann. N.Y. Acad. Sci. 1262: 85-92.
Contents: 230mg x 60 vegecaps
NeuroREGAIN is available at the following Unity Pharmacies: